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Studying the role of LPMOs in the human pathogen Cryptococcus neoformans at Københavns Universitet

Despite the importance of LPMO enzymes for pathogen virulence, we know very little in the expression patterns and biological function of these proteins.

Depending on your department and interests, the work can include working with fungal cultures in a GMO-2 laboratory, protein and enzymatic analysis by use of immuno-pull down, activity assays, western blot, determination of transcriptions profiles by the help of RT-qPCR and other.

LPMOs hold great potentials for being future drug targets against fungal pathogenesis.